Adeline Williams is an associate biological scientist at RAND. Her research focuses on how the intersection of molecular biology, emerging biotechnologies, and infectious disease epidemiology can be used to strengthen biosecurity and public health preparedness. She primarily works with the Meselson Center -- dedicated to reducing risks from biological threats and emerging technologies -- where she leverages her technical expertise to analyze pressing challenges in early detection and response to outbreaks, AI-enabled biology, and dual-use research of concern.

Prior to joining RAND, Williams was a post-doctoral, pre-doctoral, and post baccalaureate fellow at the National Institutes of Health (NIH), where she studied the molecular basis of vector-borne disease transmission, such as Zika virus and malaria, to develop novel transmission-blocking tools. She holds a Ph.D. in microbiology from Colorado State University, an MPH in infectious disease epidemiology from Yale University, and a BS/BA in Public Health and English from Tulane University. She is currently an adjunct faculty in the Biology Department at Montgomery College where she teaches Introduction to Microbiology in lecture and lab settings.

Education

PhD in microbiology, Colorado State University; MPH in epidemiology of microbial diseases, Yale School of Public Health; BS in public health, Tulane University; BA in English, Tulane University

Concurrent Non-RAND Positions

Biology Adjunct Faculty, Montgomery College

Selected Work

  • Gupta, S., Sharma, R., Williams, A.E. et al., "Global genomics of Aedes aegypti unveils widespread and novel infectious viruses capable of triggering a small RNA response," bioRxiv, 2024
  • Williams, A.E. & Olson, K.E., "Transgenic manipulation of arthropod vectors: tools to study vector-borne diseases. ," J. Vis. Exp. , 2023
  • Reid, W. R., Williams, A.E., Sanchez-Vargas, I., Lin, J., Juncu, R., Olson, K.E., Franz, A.W.E., "Assessing single-locus CRISPR/Cas9-based gene drive variants in the mosquito Aedes aegypti via single-generation crosses and modeling. ," G3 (Bethesda), 2022
  • Williams, A. E., Shrivastava, G., Gittis, A. G., Ganesan, S., Martin-Martin, I., Leon, P.C.V., Olson, K.E., Calvo, E., "Aedes aegypti Piwi4 structural features are necessary for RNA binding and nuclear localization.," Int J Mol Sci. , 2021
  • Williams, A.E., Sanchez-Vargas, I., Franz, A.W.E., Olson, K.E., "Intrathoracic inoculation of Zika virus in Aedes aegypti.," Bio-Protoc., 2021
  • Yang, L., Weiss, B.L., Williams, A.E., Aksoy, E., Orfano, A.S., Son, J.H., Wu, Y., Vigneron, A., Karakus, M., Aksoy, S., "Paratransgenic manipulation of tsetse mir275 alters the physiological homeostasis of the fly’s midgut environment.," PLoS Pathog, 2021
  • Williams, A.E., Sanchez-Vargas, I., Reid, W.R., Lin, J., Franz, A.W.E., Olson, K.E., "The antiviral small-interfering RNA pathway induces Zika virus resistance in transgenic Aedes aegypti. ," Viruses, 2020
  • Williams, A.E., Franz, AW.E., Reid, W.R, Olson, K.E., "Antiviral effectors and gene drive strategies for mosquito population suppression or replacement to mitigate arbovirus transmission by Aedes aegypti. ," Insects, 2020

Authored by Adeline Williams

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3 Results